{"id":6583,"date":"2022-02-25T16:07:24","date_gmt":"2022-02-25T08:07:24","guid":{"rendered":"http:\/\/www.jsxtsw.com\/?p=6583"},"modified":"2022-02-25T16:13:47","modified_gmt":"2022-02-25T08:13:47","slug":"%e4%b8%8d%e5%90%8c%e5%bc%ba%e5%ba%a6%e8%bf%90%e5%8a%a8%e5%af%b9%e9%ab%98%e8%84%82%e9%ab%98%e6%9e%9c%e7%b3%96%e9%a5%b2%e6%96%99%e8%af%b1%e5%af%bc%e7%9a%84%e5%a4%a7%e9%bc%a0%e9%ab%98%e8%a1%80%e7%b3%96","status":"publish","type":"post","link":"http:\/\/www.jsxtsw.com\/en\/6583\/","title":{"rendered":"\u4e0d\u540c\u5f3a\u5ea6\u8fd0\u52a8\u5bf9\u9ad8\u8102\u9ad8\u679c\u7cd6\u9972\u6599\u8bf1\u5bfc\u7684\u5927\u9f20\u9ad8\u8840\u7cd6\u3001\u9ad8\u8102\u8840\u75c7\u7684\u4fdd\u62a4\u4f5c\u7528"},"content":{"rendered":"<div class=\"MachTrans__textWrap__1NtxT MachTrans__textWrapSmall__26E1Q\">\n<div class=\"MachTrans__text__duH8w\">\n<p><span class=\"\">\u5927\u91cf\u7814\u7a76\u5df2\u7ecf\u8bc1\u5b9e\uff0csirtuin1\uff08SIRT-1\uff09\u529f\u80fd\u7684\u7834\u574f\u4e0e\u7cd6\u5c3f\u75c5\u548c\u4ee3\u8c22\u7d0a\u4e71\u6709\u5173\u3002\u672c\u5b9e\u9a8c\u7684\u76ee\u7684\u662f\u7814\u7a76\u9ad8\u5f3a\u5ea6\u95f4\u6b47\u8bad\u7ec3\uff08HIIT\uff09\u548c\u6301\u7eed\u8010\u529b\u8bad\u7ec3\uff08CET\uff09\u65b9\u6848\u5bf9\u9ad8\u8102\u9ad8\u679c\u7cd6\u996e\u98df\u8bf1\u5bfc\u7684\u7cd6\u5c3f\u75c5\u5927\u9f20\u809d\u7ec6\u80deSIRT-1\u548cPGC-1\u03b1 mRNA\u57fa\u56e0\u8868\u8fbe\u7684\u5f71\u54cd\u3002<\/span><\/p>\n<p><strong>\u5b9e\u9a8c\u65b9\u6cd5<\/strong><\/p>\n<div class=\"MachTrans__textWrap__1NtxT MachTrans__textWrapSmall__26E1Q\">\n<div class=\"MachTrans__text__duH8w\">\n<p><span class=\"\">28\u53ea\u96c4\u6027Wistar\u5927\u9f20<\/span><span class=\"\">\u88ab\u968f\u673a\u5206\u4e3a\u56db\u7ec4\uff1a\u975e\u7cd6\u5c3f\u75c5\u7ec4\uff08NDC\uff09\u3001\u9ad8\u8102\u9ad8\u679c\u7cd6\u996e\u98df\u7ec4\uff08HFD\uff09\u3001CET\u7ec4\uff08HFD-CET\uff09\u548cHIIT\u7ec4\uff08HFD-HIIT\uff09\u3002<\/span><span class=\"\">\u901a\u8fc7\u7ed9\u5927\u9f20\u5582\u98df\u9ad8\u8102\u80aa\u9ad8\u679c\u7cd6\u996e\u98df\uff0830%\u8102\u80aa\u300120%\u679c\u7cd6\u8d28\u91cf\u5360\u6bd4\uff0925\u5468\u8bf1\u5bfc\u4e8c\u578b\u7cd6\u5c3f\u75c5\u3002<\/span><span class=\"\">\u5728\u786e\u8bca\u9ad8\u8840\u7cd6\u540e\uff0cCET\u7ec4\uff0860\u201365%\u6700\u5927\u6444\u6c27\u91cf\uff09\u548cHIIT\u7ec4\uff0885\u201390%\u6700\u5927\u6444\u6c27\u91cf\uff09\u5927\u9f20\u5747\u8fdb\u884c\u4e8630\u5206\u949f\u7684\u8dd1\u6b65\u673a\u8fd0\u52a8\uff1a5\u5929\/\u5468\uff0c10\u7c73\/\u5206\u949f\uff0c\u6301\u7eed8\u5468\u3002<\/span><span class=\"\">\u6b64\u540e\uff0c\u91c7\u96c6\u8840\u6db2\u548c\u809d\u810f\u6837\u672c\u8fdb\u884c\u751f\u5316\u7814\u7a76\u3002<\/span><span class=\"\">\u4e3a\u4e86\u8fdb\u884c\u7ec4\u7ec7\u5b66\u5206\u6790\uff0c\u5c06\u809d\u810f\u56fa\u5b9a\u572810%\u798f\u5c14\u9a6c\u6797\u4e2d\uff0c\u5305\u57cb\u5728\u77f3\u8721\u4e2d\uff0c\u5207\u7247\uff085\u03bcm\u539a\uff09\u8fdb\u884cH&amp;E\u67d3\u8272\u3002<\/span><span class=\"\">\u901a\u8fc7RT-PCR\u68c0\u6d4b\u809d\u810f\u6837\u672c\u4e2dSIRT-1\u548cPGC-1\u03b1 mRNA\u7684\u8868\u8fbe\u3002<\/span><\/p>\n<p><strong>\u5b9e\u9a8c\u7ed3\u679c\u4e0e\u5206\u6790<\/strong><\/p>\n<div class=\"MachTrans__textWrap__1NtxT MachTrans__textWrapSmall__26E1Q\">\n<div class=\"MachTrans__text__duH8w\">\n<p><span class=\"MachTrans__hl__6hdYK\">\u7ed3\u679c\u8868\u660e\uff0cHIIT\u6bd4CET\u66f4\u6709\u6548\u5730\u51cf\u5c11\u56ca\u6ce1\u6027\u8102\u80aa\u53d8\u6027\u3002<\/span><span class=\"\">\u4e0eHFD\u7ec4\u76f8\u6bd4\uff0cHIIT\u7ec4\u663e\u8457\u589e\u5f3a\u4e86SIRT-1\u7684\u8868\u8fbe\uff08\u500d\u6570\u53d8\u5316\uff1a1.47\uff0cp<\/span><span class=\"\">\u2009&lt;\u2009<\/span><span class=\"\">0.047)\u3002<\/span><span class=\"\">\u7136\u800c\uff0c\u4e0eHFD\u7ec4\u76f8\u6bd4\uff0cHIIT\u964d\u4f4e\u4e86PGC-1\u03b1\u7684\u8868\u8fbe\uff0c\u4f46\u5e76\u4e0d\u663e\u8457\uff08\u500d\u6570\u53d8\u5316\uff1a1.32\u548cp<\/span><span class=\"\">\u2009&lt;\u2009<\/span><span class=\"\">0.247)\u3002<\/span><\/p>\n<div class=\"MachTrans__textWrap__1NtxT MachTrans__textWrapSmall__26E1Q\">\n<div class=\"MachTrans__text__duH8w\">\n<p><span class=\"\">\u603b\u7ed3\u6765\u8bf4\uff0c\u5728\u9ad8\u8102\u9ad8\u679c\u7cd6\u996e\u98df\u8bf1\u5bfc\u7684\u7cd6\u5c3f\u75c5\u5927\u9f20\u7684SIRT-1\u8868\u8fbe\u589e\u5f3a\u65b9\u9762\uff0cHIIT\u6bd4CET\u66f4\u6709\u6548\uff0c\u8fd9\u8868\u660e\u57282\u578b\u7cd6\u5c3f\u75c5\u7684\u60c5\u51b5\u4e0bHIIT\u53ef\u80fd\u662f\u4e00\u79cd\u6cbb\u7597\u7b56\u7565\u3002<\/span><\/p>\n<p><span style=\"font-size: 10pt; color: #808080;\">\u539f\u6587\u68c0\u7d22\uff1aOmidifar, A., Shirvani, H., Taheri, R.A. <i>et al.<\/i> Protective effects of HIIT vs. CET exercise training on high-fat-high-fructose diet-induced hyperglycemia, hyperlipidemia, and histopathology of liver in rats: regulation of SIRT1\/PGC-1\u03b1. <i>Sport Sci Health<\/i> <b>17, <\/b>707\u2013715 (2021).<br \/>\n<\/span><\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>\u5927\u91cf\u7814\u7a76\u5df2\u7ecf\u8bc1\u5b9e\uff0csirtuin1\uff08SIRT-1\uff09\u529f\u80fd\u7684\u7834\u574f\u4e0e\u7cd6\u5c3f\u75c5\u548c\u4ee3\u8c22\u7d0a\u4e71\u6709\u5173\u3002\u672c\u5b9e\u9a8c\u7684\u76ee\u7684\u662f\u7814\u7a76\u9ad8\u5f3a\u5ea6\u95f4\u6b47\u8bad\u7ec3\uff08HIIT\uff09\u548c\u6301\u7eed\u8010\u529b\u8bad\u7ec3\uff08CET\uff09\u65b9\u6848\u5bf9\u9ad8\u8102\u9ad8\u679c\u7cd6\u996e\u98df\u8bf1\u5bfc\u7684\u7cd6\u5c3f\u75c5\u5927\u9f20\u809d\u7ec6\u80deSIRT-1\u548cPGC-1\u03b1 mRNA\u57fa\u56e0\u8868\u8fbe\u7684\u5f71\u54cd\u3002 \u5b9e\u9a8c\u65b9\u6cd5 28\u53ea\u96c4\u6027Wistar\u5927\u9f20\u88ab\u968f\u673a\u5206\u4e3a\u56db\u7ec4\uff1a\u975e\u7cd6\u5c3f\u75c5\u7ec4\uff08NDC\uff09\u3001\u9ad8\u8102\u9ad8\u679c\u7cd6\u996e\u98df\u7ec4\uff08HFD\uff09\u3001CET\u7ec4\uff08HFD-CET\uff09\u548cHIIT\u7ec4\uff08HFD-HIIT\uff09\u3002\u901a\u8fc7\u7ed9\u5927\u9f20\u5582\u98df\u9ad8\u8102\u80aa\u9ad8\u679c\u7cd6\u996e\u98df\uff0830%\u8102\u80aa\u300120%\u679c\u7cd6\u8d28\u91cf\u5360\u6bd4\uff0925\u5468\u8bf1\u5bfc\u4e8c\u578b\u7cd6\u5c3f\u75c5\u3002\u5728\u786e\u8bca\u9ad8\u8840\u7cd6\u540e\uff0cCET\u7ec4\uff0860\u201365%\u6700\u5927\u6444\u6c27\u91cf\uff09\u548cHIIT\u7ec4\uff0885\u201390%\u6700\u5927\u6444\u6c27\u91cf\uff09\u5927\u9f20\u5747\u8fdb\u884c\u4e8630\u5206\u949f\u7684\u8dd1\u6b65\u673a\u8fd0\u52a8\uff1a5\u5929\/\u5468\uff0c10\u7c73\/\u5206\u949f\uff0c\u6301\u7eed8\u5468\u3002\u6b64\u540e\uff0c\u91c7\u96c6\u8840\u6db2\u548c\u809d\u810f\u6837\u672c\u8fdb\u884c\u751f\u5316\u7814\u7a76\u3002\u4e3a\u4e86\u8fdb\u884c\u7ec4\u7ec7\u5b66\u5206\u6790\uff0c\u5c06\u809d\u810f\u56fa\u5b9a\u572810%\u798f\u5c14\u9a6c\u6797\u4e2d\uff0c\u5305\u57cb\u5728\u77f3\u8721\u4e2d\uff0c\u5207\u7247\uff085\u03bcm\u539a\uff09\u8fdb\u884cH&amp;E\u67d3\u8272\u3002\u901a\u8fc7RT-PCR\u68c0\u6d4b\u809d\u810f\u6837\u672c\u4e2dSIRT-1\u548cPGC-1\u03b1 mRNA\u7684\u8868\u8fbe\u3002 \u5b9e\u9a8c\u7ed3\u679c\u4e0e\u5206\u6790 \u7ed3\u679c\u8868\u660e\uff0cHIIT\u6bd4CET\u66f4\u6709\u6548\u5730\u51cf\u5c11\u56ca\u6ce1\u6027\u8102\u80aa\u53d8\u6027\u3002\u4e0eHFD\u7ec4\u76f8\u6bd4\uff0cHIIT\u7ec4\u663e\u8457\u589e\u5f3a\u4e86SIRT-1\u7684\u8868\u8fbe\uff08\u500d\u6570\u53d8\u5316\uff1a1.47\uff0cp\u2009&lt;\u20090.047)\u3002\u7136\u800c\uff0c\u4e0eHFD\u7ec4\u76f8\u6bd4\uff0cHIIT\u964d\u4f4e\u4e86PGC-1\u03b1\u7684\u8868\u8fbe\uff0c\u4f46\u5e76\u4e0d\u663e\u8457\uff08\u500d\u6570\u53d8\u5316\uff1a1.32\u548cp\u2009&lt;\u20090.247)\u3002 \u603b\u7ed3\u6765\u8bf4\uff0c\u5728\u9ad8\u8102\u9ad8\u679c\u7cd6\u996e\u98df\u8bf1\u5bfc\u7684\u7cd6\u5c3f\u75c5\u5927\u9f20\u7684SIRT-1\u8868\u8fbe\u589e\u5f3a\u65b9\u9762\uff0cHIIT\u6bd4CET\u66f4\u6709\u6548\uff0c\u8fd9\u8868\u660e\u57282\u578b\u7cd6\u5c3f\u75c5\u7684\u60c5\u51b5\u4e0bHIIT\u53ef\u80fd\u662f\u4e00\u79cd\u6cbb\u7597\u7b56\u7565\u3002 \u539f\u6587\u68c0\u7d22\uff1aOmidifar, A., Shirvani, H., Taheri, R.A. et al. Protective effects of HIIT vs. CET exercise training on high-fat-high-fructose diet-induced hyperglycemia, hyperlipidemia, and histopathology of liver in rats: regulation of SIRT1\/PGC-1\u03b1. 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