{"id":5190,"date":"2021-01-13T15:33:10","date_gmt":"2021-01-13T07:33:10","guid":{"rendered":"http:\/\/www.ychljhotel.com\/?p=5190"},"modified":"2021-01-13T16:03:36","modified_gmt":"2021-01-13T08:03:36","slug":"%e8%83%86%e7%a2%b1%e7%bc%ba%e4%b9%8f%e9%a5%b2%e6%96%99%e8%af%b1%e5%af%bc%e5%b0%8f%e9%bc%a0%e8%82%9d%e7%99%8c%e6%a8%a1%e5%9e%8b","status":"publish","type":"post","link":"http:\/\/www.ychljhotel.com\/5190\/","title":{"rendered":"\u80c6\u78b1\u7f3a\u4e4f\u9972\u6599\u8bf1\u5bfc\u5c0f\u9f20\u809d\u764c\u6a21\u578b"},"content":{"rendered":"
\n
\n
\n
\n

\u809d\u764c\u6a21\u578b\u6240\u4f7f\u7528\u7684\u5b9e\u9a8c\u52a8\u7269\u6d89\u53ca\u5c0f\u9f20\u3001\u5927\u9f20\u3001\u8c5a\u9f20\uff0c\u6a21\u578b\u79cd\u7c7b\u4e3b\u8981\u5206\u4e3a\u5316\u5b66\u8bf1\u5bfc\u3001\u996e\u98df\u8bf1\u5bfc\u3001\u79fb\u690d\u7624\u4ee5\u53ca\u591a\u79cd\u65b9\u6cd5\u8054\u5408\u4f7f\u7528\u3002\u672c\u6587\u4e3b\u8981\u4ecb\u7ecd\u901a\u8fc7\u5316\u5b66\u548c\u996e\u98df\u8bf1\u5bfc\u7684\u5c0f\u9f20\u6a21\u578b\u3002<\/p><\/blockquote>\n

\u5316\u5b66\u8bf1\u5bfc\u6a21\u578b<\/strong><\/p>\n

\u5316\u5b66\u8bf1\u5bfc\u6a21\u578b\u7684\u4f18\u70b9\u662f\u4e0e\u4eba\u7c7b\u7684\u635f\u4f24-\u7ea4\u7ef4\u5316-\u6076\u6027\u5faa\u73af\u76f8\u4f3c\u3002\u76ee\u524d\u53d1\u73b0\u7684\u81f4\u764c\u5316\u5408\u7269\u6709\u5f88\u591a\uff0c\u5176\u4e3b\u8981\u88ab\u5206\u4e3a\u4ee5\u4e0b\u4e24\u79cd\u7c7b\u578b: \u2460\u9057\u4f20\u6bd2\u6027\u81f4\u764c\u7269\uff0c\u76f4\u63a5\u5bfc\u81f4DNA\u635f\u4f24\uff0c\u5982\u4e8c\u4e59\u57fa\u4e9a\u785d\u80fa( N-nitrosodiethylamine\uff0cDEN) \u3001\u9ec4\u66f2\u9709\u6bd2\u7d20 B(Aflatoxin B1\uff0c AFB) \u3001\u56db\u6c2f\u5316\u78b3( Carbon tetrachloride \uff0cCCl4) \u548c\u786b\u4ee3\u4e59\u9170\u80fa(Thioacetamide \uff0cTAA \u7b49; \u2461\u975e\u9057\u4f20\u6bd2\u6027\u81f4\u764c\u7269\uff0c\u4fc3\u8fdb\u7f3a\u4e4f\u76f4\u63a5\u4f5c\u7528\u9057\u4f20\u7269\u8d28\u7684\u80fd\u529b\uff0c\u4f46\u5728\u7531\u809d\u6bd2\u6027\u5316\u5408\u7269\u5f15\u53d1\u540e\u589e\u5f3a\u80bf\u7624\u5f62\u6210\u7684\u5316\u5408\u7269\uff0c\u5982\u82ef\u5df4\u6bd4\u59a5(phenobarbital\uff0cPB) \u3001\u8fc7\u6c27\u5316\u7269\u9176\u4f53\u589e\u751f\u5242(Peroxisome proliferators \uff0cPPs) \u7b49\u3002<\/p>\n

\u996e\u98df\u8bf1\u5bfc\u6a21\u578b<\/strong><\/p>\n

\u901a\u8fc7\u86cb\u6c28\u9178\u80c6\u78b1\u7f3a\u4e4f\u9972\u6599<\/span><\/a>\uff08MCD\uff09\u8bf1\u5bfc\u66f4\u4e25\u91cd\u7684\u75c5\u53d8\uff0c\u5176\u7279\u5f81\u662f1-2\u5468\u5185\u51fa\u73b0\u6025\u6027\u80f0\u817a\u708e\u548c8-10\u5468\u7684\u809d\u7ea4\u7ef4\u5316\u3002\u4e3a\u4e86\u663e\u8457\u51cf\u5c11\u81f4\u764c\u65f6\u95f4\uff0c\u4e59\u786b\u6c28\u9178\uff08ethionine\uff09\uff0c\u4e00\u79cd\u975e\u86cb\u767d\u8d28\u6027\u7ec6\u80de\u6bd2\u6027\u7532\u9178\u6a21\u62df\u7269\uff0c\u53ef\u4ee5\u6dfb\u52a0\u5230\u80c6\u78b1\u7f3a\u4e4f\u9972\u6599\u4e2d\uff08CDE\uff09\uff0c\u5582\u517b2\u5468\u5c31\u53ef\u8bf1\u5bfc\u809d\u7956\u7ec6\u80de\u7684\u5f3a\u70c8\u589e\u6b96\u548c\u809d\u661f\u72b6\u7ec6\u80de\u7684\u6d3b\u5316\uff0c\u4ece\u800c\u5f15\u8d77\u4e25\u91cd\u7684\u809d\u810f\u708e\u75c7\u3002\u8fd8\u6709\u5176\u5b83\u65b9\u5f0f\u7684\u996e\u98df\u8bf1\u5bfc\uff0c\u4f8b\u5982\u897f\u65b9\u996e\u98df\u8bf1\u5bfc\u7684\u80a5\u80d6\u7efc\u5408\u75c7\u6a21\u578b\u3001\u975e\u9152\u7cbe\u6027\u8102\u80aa\u809d\uff08NAFLD\uff09\u52a8\u7269\u6a21\u578b\u7b49\u3002<\/p>\n

\u996e\u98df\u3001\u5316\u5b66\u8bf1\u5bfc\u76f8\u5173\u7684\u5de5\u7a0b\u5c0f\u9f20<\/strong><\/p>\n

\u901a\u8fc7\u6539\u53d8\u6761\u8c03\u63a7\u809d\u764c\u7ec6\u80de\u751f\u957f\u3001\u5468\u671f\u3001\u53d1\u80b2\u7b49\u8fdb\u5c55\u7684\u57fa\u56e0\u53ef\u4ee5\u8bf1\u5bfc\u80bf\u7624\uff0c\u4f8b\u5982c-Myc\u3001Wnt\/\u03b2-catenin\u3001APC\u3001PTEN\u7b49\u3002\u57fa\u56e0\u5de5\u7a0b\u5c0f\u9f20\u5305\u62ec\u7ec4\u6210\u578b\u8868\u8fbe\u3001\u9009\u62e9\u6027\u8868\u8fbe\u3001\u4ee5\u53ca\u8bf1\u5bfc\u6027\u8868\u8fbe\u3002\u7ec4\u6210\u578b\u8868\u8fbe\u7cfb\u7edf\uff0c\u4f8b\u5982\u5b8c\u5168\u6574\u5408\u4e86\u4e59\u578b\u809d\u708e\u75c5\u6bd2X\u86cb\u767dHBx\u57fa\u56e0\u7684\u8f6c\u57fa\u56e0\u5c0f\u9f20\uff1b\u9009\u62e9\u6027\u8868\u8fbe\u7cfb\u7edf\uff0c\u4f8b\u5982\u5229\u7528Cre\/loxP\u91cd\u7ec4\u7cfb\u7edf\u6784\u5efa\u7684Alb\/c-myc\u548c MT\/TGF-\u03b1\u8f6c\u57fa\u56e0\u5c0f\u9f20\uff1b\u8bf1\u5bfc\u6027\u8868\u8fbe\u7cfb\u7edf\uff0c\u4f8b\u5982\u5229\u7528\u56db\u73af\u7d20\u8c03\u63a7\u57fa\u56e0\u8868\u8fbe\u7cfb\u7edf\u6784\u5efa\u7684LAP-tTA\u548cTRE-MYC\u5c0f\u9f20\u3002<\/p>\n

\u57fa\u56e0\u5de5\u7a0b\u5c0f\u9f20\u996e\u98df+\u5316\u5b66\u8bd5\u5242\u8bf1\u5bfc\u64cd\u4f5c\u65b9\u6cd5<\/span><\/p>\n

LAP-tTA\u548cTRE-MYC\u5c0f\u9f20\uff0c\u5728\u53bb\u9664\u53cc\u8f6c\u57fa\u56e0\u5c0f\u9f20\u996e\u7528\u6c34\u4e2d\u7684\u5f3a\u529b\u9709\u7d20(100\u03bcg\/ml)\u540e\uff0c\u809d\u810fMYC\u8868\u8fbe\u88ab\u6fc0\u6d3b\uff1bC57BL\/6\u5c0f\u9f20\u4ee520\u03bcg\/g\u4f53\u91cd\u8179\u8154\u6ce8\u5c04\u4e8c\u4e59\u57fa\u4e9a\u785d\u57fa\u80fa(DEN)\u5efa\u7acb\u5316\u5b66\u8bf1\u5bfc\u6027HCC\u300212\u5468\u9f84\u96c4\u6027B6.Cg-Lepob<\/sup>\/J (ob\/ob) \u5c0f\u9f20\u5728\u7279\u5b9a\u65f6\u95f4\u5582\u98df\u86cb\u6c28\u9178\u80c6\u78b1\u7f3a\u4e4f\u9972\u6599\uff08MCD\uff09\u3001\u80c6\u78b1\u7f3a\u4e4f\u6c28\u57fa\u9178\u9972\u6599\uff08CDAA\uff09\u3001\u9ad8\u8102\u80aa\u9972\u6599\uff08HF\uff09\uff0c\u8bf1\u5bfcNAFLD\uff0cMCD\u9972\u6599\u4e2d\u6dfb\u52a0\u7389\u7c73\u6cb9(10%)\uff0c\u4e0d\u6dfb\u52a0\u9c7c\u6cb9\u3002\u6539\u826f\u540e\u7684\u9972\u6599\u4ee5AIN-76A\u6807\u51c6\u9972\u6599\u4e3a\u57fa\u7840\uff0c\u70ed\u91cf\u7b49\u9ad8(4.45\u5343\u5361\/\u514b)\uff0c\u8102\u80aa\u542b\u91cf\u76f8\u540c(23%)\u3002\u4ee5\u4e0d\u540c\u6bd4\u4f8b\u4f9b\u5e94\u5bcc\u542b\u4e9a\u6cb9\u9178\u7684\u7ea2\u82b1\u6cb9\u548c\u542b\u9971\u548c\u8102\u80aa\u9178\u7684\u6930\u5b50\u6cb9\uff0c\u4f4e\u4e9a\u6cb9\u9178\u996e\u98df\u542b\u91cf\u4e3a2%\uff0c\u9ad8\u4e9a\u6cb9\u9178\u996e\u98df\u542b\u91cf\u4e3a12%\u3002\u91c7\u7528\u9ad8\u4e9a\u6cb9\u9178\u6216\u4f4e\u4e9a\u6cb9\u9178\u9972\u5582C57BL\/6\u5c0f\u9f204\u5468\u3002<\/p>\n

MYC\u8fc7\u8868\u8fbe\u7684\u5c0f\u9f20\uff0cMCD\/CDAA\/HF\u9972\u6599\u5582\u517b\uff0c\u7ed9\u4e88\u6216\u662f\u4e0d\u7ed9\u4e88DEN\u5582\u517b\u3002\"\"<\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

\n
\n
\n
\n
\u6587\u7ae0\u6765\u6e90\uff1a\u5e93\u57fa\u751f\u7269cookgen<\/span><\/p>\n
<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n
\n
\n
\n
\n
\n
\n
\n
<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n
\n
<\/section>\n<\/section>\n<\/section>\n
\n
\n
<\/section>\n<\/section>\n
\n
\n
\n
<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n
\n
<\/section>\n<\/section>\n
\n
\n
<\/section>\n<\/section>\n
\n
\n
\n
<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n
<\/section>\n
\n
\n
\n
\n
\n
\n
\n
<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n
<\/section>\n<\/section>\n
\n
<\/section>\n<\/section>\n","protected":false},"excerpt":{"rendered":"

\u809d\u764c\u6a21\u578b\u6240\u4f7f\u7528\u7684\u5b9e\u9a8c\u52a8\u7269\u6d89\u53ca\u5c0f\u9f20\u3001\u5927\u9f20\u3001\u8c5a\u9f20\uff0c\u6a21\u578b\u79cd\u7c7b\u4e3b\u8981\u5206\u4e3a\u5316\u5b66\u8bf1\u5bfc\u3001\u996e\u98df\u8bf1\u5bfc\u3001\u79fb\u690d\u7624\u4ee5\u53ca\u591a\u79cd\u65b9\u6cd5\u8054\u5408\u4f7f\u7528\u3002 […]<\/p>\n","protected":false},"author":3,"featured_media":5192,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[10],"tags":[392],"_links":{"self":[{"href":"http:\/\/www.ychljhotel.com\/wp-json\/wp\/v2\/posts\/5190"}],"collection":[{"href":"http:\/\/www.ychljhotel.com\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www.ychljhotel.com\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www.ychljhotel.com\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"http:\/\/www.ychljhotel.com\/wp-json\/wp\/v2\/comments?post=5190"}],"version-history":[{"count":0,"href":"http:\/\/www.ychljhotel.com\/wp-json\/wp\/v2\/posts\/5190\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/www.ychljhotel.com\/wp-json\/wp\/v2\/media\/5192"}],"wp:attachment":[{"href":"http:\/\/www.ychljhotel.com\/wp-json\/wp\/v2\/media?parent=5190"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www.ychljhotel.com\/wp-json\/wp\/v2\/categories?post=5190"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.ychljhotel.com\/wp-json\/wp\/v2\/tags?post=5190"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}亚洲偷自拍页,亚洲日韩小说自拍,自拍偷区亚洲国内自拍蜜臀,欧美另类亚洲卡通自拍 (function(){ var bp = document.createElement('script'); var curProtocol = window.location.protocol.split(':')[0]; if (curProtocol === 'https') { bp.src = 'https://zz.bdstatic.com/linksubmit/push.js'; } else { bp.src = 'http://push.zhanzhang.baidu.com/push.js'; } var s = document.getElementsByTagName("script")[0]; s.parentNode.insertBefore(bp, s); })();